Following years of futile attempts, new research from the Monell Center demonstrates that living human taste cells can be maintained in culture for at least seven months. The findings provide scientists with a valuable tool to learn about the human sense of taste and how it functions in health and disease.
This advance ultimately will assist efforts to prevent and treat taste loss or impairment due to infection, radiation, chemotherapy and chemical exposures.
“People who undergo chemotherapy or radiation therapy for oral cancer often lose their sense of taste, leading to decreased interest in food, weight loss, and malnutrition,” said lead author M. Hakan Ozdener, M.D., Ph.D., M.P.H., a cellular biologist at Monell. “The success of this technique should provide hope for these people, as it finally provides us with a way to test drugs to promote recovery.”